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According to Anna Need, Ph.D, schizophrenia researcher and assistant professor in the Center for Human Genome Variation at Duke University, it tells us that in those particular studies… A new study in rodents has demonstrated, for the first time, that the brain’s cerebellum plays a role in controlling reward and social preference behavior—findings that shed light on the brain circuits critical to the affective and social dysfunction seen across multiple psychiatric disorders. is a service of the American Association for the Advancement of Science. Studies with the most recent start date appear first. 8 This implies that … EurekAlert! view more, Credit: E. Onwordi at MRC London Institute of Medical Sciences (LMS). Schizophrenia may result in some combination of hallucinations, delusions, and extremely disordered thinking and behavior that impairs daily functioning, and can be disabling. After being injected, the tracer binds specifically to a protein found in synapses called SV2A (synaptic vesicle glycoprotein 2A), which has been shown in animal and post-mortem studies to be a good marker of the density of synaptic nerve endings in the brain. A new schizophrenia treatment is being developed that relies on interactions and relationships has been successful in treating adolescents who are showing early symptoms of schizophrenia. However, several recent studies have found no evidence for an association between OCs and risk for schizophrenia [26, 27]. Credit: E Onwardi, at MRC London Institute of Medical Sciences. Life expectancy in schizophrenia has failed to improve over recent decades. Mice with an impaired version of one the few genes definitively linked to schizophrenia showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients. ", "Having scans that can characterise the distribution of the approximately 100 trillion synapses in the living brain, and find differences in their distribution between people with and without schizophrenia, represents a significant advance in our ability to study schizophrenia.". Recent Schizophrenia Research Articles. One study even linked first generation antipsychotic drugs to the loss of brain tissue in people with schizophrenia. However, researchers had only been able to study this indirectly, such as in post mortem brains samples, or animal and cell models in the lab. "We need to develop new treatments for schizophrenia. Hilary Jones The National Institute of Mental Health (NIMH) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services. Star-shaped support brain cells, astrocytes, growing in 3-D “organoids” in a dish develop similarly as those in human brain tissue. provides eligible reporters with free access to embargoed and breaking news releases. A new study shows that young people with first episode psychosis have a much higher death rate than previously thought. Study Makes Case for Rigorous Re-Testing of Opioid Antagonists to Treat Schizophrenia . Drugs Targeting the Glutamate System Warrant Continued Development for Schizophrenia, Study Finds. Advances in scanning have allowed researchers for the first time to show lower levels of a protein found in the connections between neurons in the living brains of people with schizophrenia. Recent work by Howes and colleagues found that in the earliest stages of schizophrenia, people experience a surge in the number and activity of immune cells in the brain. 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